What was the contribution of Rudolf Weigl?   

Alfred Evans
@Alfred.Evans · Posted 06 Sep. 2021

Jack Penn
@Jack.Penn · Posted 06 Sep. 2021

Rudolf Stenfan Jan Weigl is known by his short name Rudolf Weigl. He was born on 2nd September 1883 in Prerau. His father has passed away when he was a child due to a bicycle accident. After his father’s unfortunate death his mother, Elisabeth Kroesel married Jozef Trohnar who was a secondary school teacher. Weigl was ennobled in Jaslo, a place in Poland, but he was always a fluent German speaker. When he moved with his family to Poland, there he started adopting the language and their culture. He contributed a lot to humankind by his innovation till the last day of his life; he passed away on 11 August in the year 1957. Dr. Weigl was a polished physician, biologist, and a great inventor. He was well known for his great invention of the first vaccine for the epidemic typhus. Rudolf Weigl's vaccine was highly effective against the epidemic typhus. He was respectively nominated for Nobel Prize because of his huge contribution towards life between the years 1930-1939. Rudolf had worked hard during this Holocaust to protect several lives from different countries against the pandemic typhus by his great creation of vaccines. Also, he gave shelter to those people who were suffering under Nazis in occupied Poland. He was respectively named Righteous in the whole Nation due to his eminent contribution towards the lives in 2003.

 In the year 1930, following the discovery of Charles Nicolle in 1990, it became known that lice were the real vector of this typhus, and also work had been done on vaccines related to Rocky Mountain Spotted fever. Rudolf Weigl took this creation to the next level and established a different as well effective technique to generate the typhus vaccine by raising infected lice also crunching them into the vaccine paste. Dr. Weigl discovered that this vaccine which could be exhibited from the lice stomachs transited with the Rickettsia Prowazeki, who was a causative agent of this typhus. He successfully developed the initial version of this vaccine in the year 1918 & started his experiment with this vaccine by applying it on pigs and also even on human volunteers. He was working with this technique until the year 1933; then he actually successfully performed its testing on a large scale to experiment with lice and cultivate bacteria by using the strategy of micro infection. This method is comprised of four major steps:

1.       Growing healthy lice at least for 12 days

2.      Injecting these lice with typhus

3.      Growing them a little more, for additional 5 days

4.      Extracting those lice’s midgets then grind them into the paste ( that was a vaccine)


It was written in Rudolf Weigl Biography that how Dr. Weigl contributed towards humankind through his innovative creation of this vaccine against the pandemic typhus. His great contribution was honored differently like he got nominations for the Nobel Prize for the year between 1930 to 1939.

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